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In conjunction with appropriate staining, laser capture microdissection (LCM) enables very specific targeting of cell types. Our in-house pathologist leads our LCM team that has extensive experience with tissue sectioning, staining, and capturing target cells. We use a Zeiss PALM system to image, cut and catapult target cells. Before and after images of the tissue section are stored and used for QC pass/fail determination. Gene Logic’s RNA isolation team use optimized and validated protocols and prepare RNA for successful gene expression analysis.

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We purify DNA and RNA from multiple types of samples. Our extensive experience with a range of sample types allows us to select/recommend the protocols needed to meet downstream processing needs. Sample availability is not always ideal, the sample may be in limited quantities or may have been collected in sub-optimal conditions. We have successfully processed many samples like these, optimizing protocols depending on the situation. Following purification, we determine quantity and quality with NanoDrop and Agilent Bioanalyzer platforms.

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Since 1995 Gene Logic has been performing genomic services for clients. Our experience is unrivalled. From study design through to report analysis. From skin biopsy samples to laser captured cells. From basic research projects to clinical trials. From RNA isolation only projects to coordinating multi-site clinical trials. From your lab to ours, Gene Logic is able to help.

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